0001888886 2026-05-06 2026-05-06 0001888886 1 2026-05-06 2026-05-06 0001888886 2 2026-05-06 2026-05-06 iso4217:USD pure S-3 424B5 EX-FILING FEES 333-289326 0001888886 Structure Therapeutics Inc. N/A N/A S-3 Structure Therapeutics Inc. false Equity Ordinary Shares, $0.0001 par value per share true 150000000.00 0.0001381 20715.00 true Equity Ordinary Shares, $0.0001 par value per share true 250000000.00 38275.00 400000000.00 58990.00 38275.00 0.00 20715.00 The proposed maximum aggregate offering price is being used to calculate the registration fee pursuant to Rule 457(o) under the Securities Act of 1933, as amended. On August 6, 2025, the registrant filed a prospectus (the "Prospectus") with the Securities and Exchange Commission as part of its registration statement on Form S-3ASR (File No. 333-289326) (the "Registration Statement"), relating to the offer and sale of its American Depositary Shares ("ADSs"), each representing three ordinary shares, $0.0001 par value per ordinary share, having an aggregate offering price of up to $250,000,000 pursuant to the terms of a sales agreement. The registrant is amending the Prospectus to increase the aggregate offering price by $150,000,000 in the aggregate, excluding the $250,000,000 previously registered. The fee is calculated in accordance with Rule 456(b) and Rule 457(r) of the Securities Act of 1933, as amended. This "Calculation of Registration Fee" table shall be deemed to update the "Calculation of Registration Fee" table in the registrant's Registration Statement. See note 1. The registrant previously paid a registration fee of $38,275.00 in connection with the filing of the Prospectus. 400000000.00 true